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CNB-001

SKU: orb2566613

Description

CNB-001 is a research compound that potently inhibits 5-lipoxygenase (5-LOX), reducing its expression and enhancing proteasome activity. In Alzheimer's disease models, it modulates eIF2α phosphorylation, HSP90, and ATF4 to limit Aβ and aggregated proteins, while preserving synaptic markers and improving memory, making it valuable for neurodegenerative disease research.

Research Area

Metabolism Research, Signal Transduction

Images & Validation

Key Properties

CAS Number1019110-87-2
MW440.49
FormulaC27H24N2O4
SMILESC(=C/C1=CC(OC)=C(O)C=C1)\C=2N(N=C(/C=C/C3=CC(OC)=C(O)C=C3)C2)C4=CC=CC=C4
TargetLipoxygenase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information