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COB-187

SKU: orb2646381

Description

COB-187 is a potent, selective, and ATP-competitive GSK-3β inhibitor that acts via reversible engagement of Cys-199. This small molecule has demonstrated utility in cellular research, suppressing LPS-induced cytokine and SARS-CoV-2 spike protein-triggered CXCL10 production in vitro.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number1862177-86-3
MW302.41
FormulaC15H14N2OS2
SMILESS=C1SCC(O)(C=2C=CC=CC2)N1CC=3C=CN=CC3
TargetGSK-3

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information