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Cycloguanil hydrochloride

SKU: orb1220994

Description

Cycloguanil is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodium and human forms respectively).

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number152-53-4
MW288.18
Purity>98% (HPLC)
FormulaC11H14ClN5.ClH
SMILESCl.CC1(C)N=C(N)N=C(N)N1c1ccc(Cl)cc1
TargetParasite
SolubilityDMSO: 20 mg/mL (69.4 mM);Water: 5 mg/mL (17.35 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Chloroguanide Triazine

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Cycloguanil hydrochloride (orb1220994)

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Available Sizes

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200 mg
500 mg
2 mg
¥ 1,300.00
5 mg
¥ 1,690.00
10 mg
¥ 2,470.00
25 mg
¥ 3,900.00
50 mg
¥ 6,500.00
100 mg
¥ 9,490.00