Cyproheptadine hydrochloride sesquihydrate

SKU: orb1310871

Description

Cyproheptadine hydrochloride sesquihydrate (Peritol) is a small molecule antagonist of serotonin and histamine H2 receptors. It is widely used in pharmacological research for in vitro receptor binding studies and in vivo models investigating allergy, appetite regulation, and serotonin-mediated pathways.

Research Area

Epigenetics & Chromatin, Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	41354-29-4
MW	341.88
Purity	>99.99% (May vary between batches)
Formula	C₂₁H₂₄ClNO
SMILES	O.O.O.Cl.Cl.CN1CC\C(CC1)=C1/c2ccccc2C=Cc2ccccc12.CN1CC\C(CC1)=C1/c2ccccc2C=Cc2ccccc12
Target	Histamine Receptor,5-HT Receptor,Histone Methyltransferase
Solubility	DMSO:70 mg/mL (204.75 mM);Ethanol:20 mg/mL (58.5 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (7.31 mM)

Bioactivity

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Target IC50	SETD7/9:1 μM\|5-HT2:0.6 nM

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Periactin hydrochloride, SETD9, SETD7, Cyproheptadine hydrochloride sesquihydrate, 5-HT2, 5-HT Receptor, 5HT Receptor, 5HTReceptor, HistamineReceptor, Histamine Receptor, HistoneMethyltransferase, Histone Methyltransferase

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Compound Identifiers

PubChem CID

11954233 ↗

Key Properties

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No computed properties available.

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