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Cystatin B agonist 1

SKU: orb3136395

Description

Cystatin Bagonist 1 is an orally active inhibitor of MMP-2/9. It suppresses U87 and T98G cells with IC50 values of 3.95 μM and 3.43 μM, respectively. Cystatin Bagonist 1 induces S-phase cell cycle arrest in MG cells and inhibits their angiogenesis, migration, and invasion. Additionally, it hinders tumor growth in U87 MG xenograft models. This compound is applicable for research in malignant glioma (MG).

Research Area

Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction

Images & Validation

Key Properties

TargetCadherin,MMP

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information