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D2R/D3R/5-HT1AR agonist 1

SKU: orb3174262

Description

D2R/D3R/5-HT1AR agonist 1 (compound 22b) is an orally active tri-target agonist with EC50 values of 1.29, 1.05, and 153.5 nM for D2R, D3R, and 5-HT1AR receptors, respectively. This compound improves MPTP-induced behavioral disorders and exhibits antidepressant properties, making it relevant for research in Parkinson's disease and depression.

Images & Validation

Key Properties

CAS Number3028684-07-0
MW421.6
FormulaC21H35N5O2S
SMILESN(CC1CCN(C(=O)N2CCOCC2)CC1)(CCC)[C@@H]3CC4=C(CC3)N=C(N)S4
TargetDopamine Receptor,5-HT Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information