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D3R/MOR antagonist 2

SKU: orb2278411

Description

Compound 121 is a dual D3 receptor antagonist (K i = 361 nM) and mu-opioid receptor antagonist/partial agonist (K i = 85.2 nM). This profile suggests utility in preclinical research for investigating novel analgesic mechanisms with potentially reduced abuse liability, applicable in both in vitro binding assays and in vivo behavioral models.

Research Area

Metabolism Research, Neuroscience, Neuroscience; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery

Images & Validation

Key Properties

MW410.98
FormulaC25H31ClN2O
TargetDopamine Receptor,Opioid Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information