Deglycobleomycin

SKU: orb3135266

Description

Deglycobleomycin is an RNA cleaving agent that targets r(CUG) repeat sequences. By binding with small molecules that recognize r(CUG)exp, Deglycobleomycin can selectively cleave r(CUG)exp. Its efficiency in cleaving DNA is considerably lower than that of Bleomycin A5(Pingyangmycin), but it exhibits enhanced selectivity for r(CUG)exp. Deglycobleomycin is useful for research on diseases associated with r(CUG) repeat expansions, such as myotonic dystrophy type 1, and the development of drugs aimed at precise targeting and cleavage of pathogenic RNA.

Images & Validation

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Key Properties

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CAS Number	78314-57-5
MW	1058.20
Formula	C₄₂H₆₃N₁₉O₁₀S₂
SMILES	[C@H](NC[C@@H](C(N)=O)N)(CC(N)=O)C=1N=C(C(N[C@@H]([C@@H](O)C2=CN=CN2)C(N[C@@H]([C@H]([C@@H](C(N[C@H](C(NCCC3=NC(=CS3)C4=NC(C(NCCCCNC(=N)N)=O)=CS4)=O)[C@@H](C)O)=O)C)O)C)=O)=O)C(C)=C(N)N1
Target	DNA/RNA Synthesis

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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DNA/RNA Synthesis

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