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Deoxynivalenol

SKU: orb1707387

Description

Deoxynivalenol (Vomitoxin) is a Fusarium mycotoxin from the trichothecene family that contaminates food and feed. It crosses intestinal tight junctions via a cellular bypass, unaffected by PgP or MRP inhibitors, and induces gastrointestinal effects like diarrhea and inflammation. This compound is widely used in toxicology research for studying mycotoxin exposure in both in vitro cellular models and in vivo animal studies.

Images & Validation

Key Properties

CAS Number51481-10-8
MW296.32
Purity99.47% (May vary between batches)
FormulaC15H20O6
SMILESCC1=C[C@H]2O[C@@H]3[C@H](O)C[C@@](C)([C@]33CO3)[C@@]2(CO)[C@H](O)C1=O
TargetOthers
SolubilityDMSO:260 mg/mL (877.43 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (16.87 mM)

Bioactivity

Target IC50
IPEC-J2 cells:25.93 ± 5.13 μM (72 h)|IPEC-J2 cells:44.83 ± 6.14 μM (48 h)|COLO 201 cells:86 μM|K562 cells:1010 nM (EC50)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

4-Deoxynivalenol, Deoxynivalenol, Vomitoxin

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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1 mg
$ 130.00
5 mg
$ 370.00
10 mg
$ 590.00
DispatchUsually dispatched within 5-10 business days
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