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Deschloroclozapine dihydrochloride

SKU: orb3137000

Description

Deschloroclozapine dihydrochloride, a metabolite of clozapine, is a potent agonist for muscarinic DREADDs. It binds to the DREADD receptor subtypes hM3Dq and hM4Di with Ki values of 6.3 and 4.2 nM, respectively. [11C]-Deschloroclozapine is a promising PET tracer for imaging DREADDs.

Research Area

Neuroscience

Images & Validation

Key Properties

MW365.30
FormulaC18H22Cl2N4
SMILESCN(CC1)CCN1C2=NC(C=CC=C3)=C3NC4=C2C=CC=C4.Cl.Cl
TargetAChR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information