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DHICA

SKU: orb2802468

Description

DHICA (5,6-Dihydroxyindole-2-carboxylic acid) is an intermediate in melanin synthesis and a component of eumelanin, as well as acting as a moderate potency agonist of GPR35. In the U2OS cell line, DHICA demonstrates the ability to induce β-arrestin translocation signaling with an EC50 value of 23.2 μM. Additionally, it plays a significant role in promoting and protecting against DNA damage.

Images & Validation

Key Properties

CAS Number4790-08-3
MW193.16
FormulaC9H7NO4
SMILESO=C(O)C1=CC=2C=C(O)C(O)=CC2N1
TargetArrestin,Endogenous Metabolite

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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DHICA (orb2802468)

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