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DLK-IN-1

SKU: orb1709857

Description

DLK-IN-1 is a potent, selective, and brain-penetrant oral inhibitor of DLK (MAP3K12) with a Ki of 3 nM. It demonstrates in vivo efficacy in Alzheimer's disease models and is utilized in research on neurodegenerative pathways and kinase inhibition.

Research Area

Molecular Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number1620574-24-4
MW423.43
FormulaC20H24F3N5O2
SMILES[H][C@@]12CN(C[C@]1([H])[C@H]2c1cc(nn1C(C)C)-c1cnc(N)c(OC(F)(F)F)c1)C1COC1
TargetDNA Alkylation

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information