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Doxapram hydrochloride

SKU: orb3174703

Description

Doxapram (hydrochloride) is a respiratory stimulant. It inhibits the function of TASK tandem pore (K2P) potassium channels, with EC50 values of 410 nM for TASK-1 and 37 nM for TASK-3. The compound displays an EC50 of 9 μM in inhibiting TASK-1/TASK-3 heterodimer channel function. Doxapram (hydrochloride) can be used in research on apnea in premature infants.

Images & Validation

Key Properties

CAS Number113-07-5
MW414.97
FormulaC24H31ClN2O2
SMILESCl.O=C1N(CC)CC(CCN2CCOCC2)C1(C=3C=CC=CC3)C=4C=CC=CC4
TargetPotassium Channel

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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