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DYRKs-IN-1

SKU: orb1709813

Description

DYRKs-IN-1 is a potent and selective small molecule inhibitor of DYRK1A and DYRK1B kinases, exhibiting IC50 values of 5 nM and 9 nM, respectively. It demonstrates antitumor properties and is a valuable chemical probe for studying DYRK family functions in cancer biology, cell cycle regulation, and neurodegenerative disease research in both cellular and animal models.

Research Area

Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number1387090-01-8
MW588.06
FormulaC30H30ClN7O4
SMILESO=C1N=C2NC(N3CC4OC(C3)CC4)=NC=C2C=C1C(NC5=CC(C(NC(CCN)C6=CC=CC=C6)=O)=CC=C5Cl)=O
TargetDYRK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information