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EDP-305

SKU: orb1744190

Description

EDP-305 is a potent and selective oral FXR agonist, demonstrating EC50 values of 34 nM and 8 nM in different cellular assays. It shows consistent antifibrotic activity in research models for liver diseases, including primary biliary cholangitis (PBC) and non-alcoholic steatohepatitis (NASH), as supported by in vitro and in vivo studies.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number1933507-63-1
MW630.92
Purity97.17% (May vary between batches)
FormulaC36H58N2O5S
SMILESO[C@H]1[C@@]2([C@@]([C@]3(C)[C@]([C@H]1CC)(C[C@H](O)CC3)[H])(CC[C@@]4(C)[C@]2(CC[C@@]4([C@@H](CCNC(NS(=O)(=O)C5=CC=C(C(C)(C)C)C=C5)=O)C)[H])[H])[H])[H]
TargetOthers,Phosphatase,FXR,Cytochromes P450

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 160.00
5 mg
$ 330.00
1 ml x 10 mM (in DMSO)
$ 440.00
10 mg
$ 540.00
25 mg
$ 1,030.00
50 mg
$ 1,630.00
100 mg
$ 2,540.00
DispatchUsually dispatched within 6-8 weeks
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