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β-Endorphin (1-27) (human)

SKU: orb2276966

Description

This synthetic peptide is an opioid receptor antagonist with high affinity for μ- (Ki=5.31 nM), δ- (Ki=6.17 nM), and κ-opioid (Ki=39.82 nM) receptors. It is a valuable research tool for studying opioid-mediated analgesia and receptor function in both in vitro binding assays and in vivo pain modulation studies.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

TargetOpioid Receptor
CAS Number76622-84-9
MW3022.47
FormulaC139H217N33O40S
SMILESC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC(CNC(CNC([C@H](CC2=CC=C(O)C=C2)N)=O)=O)=O)=O)CCSC)=O)[C@@H](C)O)=O)CO)=O)CCC(O)=O)=O)CCCCN)=O)CO)=O)CCC(N)=O)=O)[C@@H](C)O)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CC=C(O)C=C5)C(O)=O)=O)C)=O)CC(N)=O)=O)CCCCN)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)C)=O)CC(N)=O)=O)CCCCN)=O)=O)CC(C)C)=O)[C@@H](C)O)=O)C(C)C)=O)CC(C)C)=O)CCC3

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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