EWS RNA binding protein 1 Antibody

SKU: orb3148694

Description

Goat polyclonal antibody to EWSR1. EWSR1, or Ewing Sarcoma Breakpoint Region 1, encodes the EWS protein, a member of the FET (FUS, EWS, TAF15) family of RNA-binding proteins. These proteins are involved in various cellular processes, including gene transcription and RNA splicing. The EWS protein has a transcriptional activation domain that initiates gene transcription and an RNA-binding domain that attaches to RNA molecules. This dual functionality suggests a role in both transcription regulation and RNA processing.

Research Area

Cancer Biology

Images & Validation

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Tested Applications	WB
Dilution Range	WB:1:500-1:2,000
Reactivity	Canine, Human, Monkey, Mouse, Rat
Application Notes	The antibody solution should be gently mixed before use.

Key Properties

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Host	Goat
Clonality	Polyclonal
Isotype	IgG
Immunogen	Antigen: Purified recombinant peptide derived from within residues 140 aa to the N-terminus of human EWSR1 produced in E. coli. Antigen Sequence: MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQPAAT
Purification	Epitope affinity purified
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Form/Appearance	Polyclonal antibody supplied as a 100 µl (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide.
Concentration	Please inquire
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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EWS, EWS-FLI1, bK984G1.4 antibody.

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Protocol Information

Western Blot (IB, immunoblot)

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