EZH2 (N) Antibody, Rabbit Polyclonal

SKU: orb66894

Description

Rabbit polyclonal to EZH2.Enhancer of zeste homolog 2 (EZH2) belongs to the Polycomb-group (PcG) family. Members fromthis family form multimeric protein complexes, which play a role in maintaining the transcriptionalrepressive state of genes over successive cell generations. EZH2 interacts with the embryonicectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. The complexit forms with EED/PRC2 promotes the methylation of Lys-9 and Lys-27 of histone H3, which in turnleads to the transcriptional repression of the target genes.

Research Area

Epigenetics

Images & Validation

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Item 1 of 1

Tested Applications	WB
Dilution range	WB:1:1000-1:5000
Reactivity	Human

Key Properties

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Host	Rabbit
Clonality	Polyclonal
Immunogen	N-terminal region of human EZH2
Molecular Weight	85
Purity	Affinity purification
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives	0.01% NaN3
Disclaimer	For research use only

Alternative Names

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anti-EZH2 antibody,anti-ENX1 antibody,anti-ENX1 antibody,anti-EZH1 antibody,anti-KMT6 antibody,anti-KMT6A antibody,anti-MGC9169 antibody,anti-Histonelysine Nmethyltransferase EZH2 antibody,anti-LysineNmethyltransferase 6 antibody

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Western blot analysis of total cell extracts from human Hela using EZH2 antibody

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UniProt

Q15910

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No UniProt data available

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Protocol Information

Western Blot (IB, immunoblot)

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