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Flibanserin

SKU: orb1302975

Description

Flibanserin (Girosa) is a serotonergic agent approved for hypoactive sexual desire disorder. It is used in neuroscience research to study serotonin receptor modulation in vitro and in vivo. While minor serum enzyme elevations have been reported, it is not associated with clinically significant liver injury.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number167933-07-5
MW390.4
Purity99.76% (May vary between batches)
FormulaC20H21F3N4O
SMILESC(CN1CCN(CC1)C2=CC(C(F)(F)F)=CC=C2)N3C=4C(NC3=O)=CC=CC4
TargetDopamine Receptor|||5-HT Receptor
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.12 mM);DMSO:50 mg/mL (128.07 mM)

Bioactivity

Target IC50
D4 receptor:4-24 nM(Ki)|5-HT2A:49 nM(Ki)|5-HT1A:1 nM(Ki)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

desire, disorder, DopamineReceptor, Dopamine Receptor, DP1, DP2, D4, 5-hydroxytryptamine Receptor, 5HTReceptor, affinity, 5-HT2A, 5-HT Receptor, 5-HT1A, 5HT Receptor, BIMT 17, BIMT17, BIMT-17, BIMT-17BS, antidepressant, antianxiety, Girosa, Flibanserin, Inhibitor, hypoactive, hypoactive sexual desire disorder, hippocampus, HSDD, midbrain, neurotransmitter, NHSF cell line, no cytotoxicity, orally active, inhibit, prefrontal cortex, sexual, Serotonin Receptor

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 ml x 10 mM (in DMSO)
$ 80.00
5 mg
$ 80.00
10 mg
$ 100.00
25 mg
$ 150.00
50 mg
$ 240.00
100 mg
$ 360.00
500 mg
$ 800.00
DispatchUsually dispatched within 3-5 working days
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