Fluoxetine hydrochloride

SKU: orb1310602

Description

Fluoxetine hydrochloride (Lilly 110140) is a selective serotonin reuptake inhibitor (SSRI) used as an antidepressant with a favorable side-effect profile. It is widely employed in neuroscience research to study serotonin neurotransmission in both in vitro binding assays and in vivo behavioral models of depression.

Research Area

Pharmacology & Drug Discovery

Images & Validation

−

Key Properties

−

CAS Number	56296-78-7
MW	345.787
Purity	99.98% (May vary between batches)
Formula	C₁₇H₁₉ClF₃NO
SMILES	Cl.CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1
Target	Serotonin Transporter,Autophagy,5-HT Receptor
Solubility	H2O:3.5 mg/mL (10.12 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.57 mM);DMSO:127 mg/mL (367.28 mM)

Bioactivity

−

In Vivo

Fluoxetine accelerates the maturation of immature neurons. It enhances the proliferation of new cells in the dentate gyrus of the adult rat hippocampus, strengthens neurodependent long-term potentiation in the hippocampal dentate gyrus, and increases the number of proliferating cells in the prefrontal cortex.

Storage & Handling

−

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

−

5-HT, 5-HTT, 5HTReceptor, 5HT Receptor, Autophagy, inhibit, Lilly110140, LY110140, LY-110140, LY 110140, Fluoxetine, Fluoxetine HCl, Fluoxetine hydrochloride, Fluoxetine Hydrochloride, Inhibitor, SLC6A4, Serotonin Transporter, SerotoninTransporter, Sert (Sodium-dependent), SERT

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Compound Identifiers

PubChem CID

62857 ↗

Key Properties

−

No computed properties available.

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols