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FOXJ1 agonist 1

SKU: orb2665311

Description

FOXJ1 agonist 1 (compound 16c) is an orally bioavailable small molecule that upregulates FOXJ1 to promote motile ciliogenesis in airway multiciliated cells. It demonstrates protective efficacy in elastase-induced COPD mouse models and exhibits favorable pharmacokinetic properties with low CYP/hERG inhibition and cytotoxicity, supporting its use in respiratory disease research.

Research Area

Cell Biology, Signal Transduction

Images & Validation

Key Properties

MW433.5
FormulaC24H27N5O3
TargetNF-κB,Others,FOXO

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

FOXJ1 agonist 1 (orb2665311)

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