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FPR Agonist 43

SKU: orb1706571

Description

FPR Agonist 43 is a synthetic small molecule that simultaneously activates both formyl peptide receptor 1 (FPR1) and FPR2/ALX. This dual agonist is a valuable research tool for investigating receptor-specific signaling, immune cell chemotaxis, and inflammation in both cellular and animal models of disease.

Research Area

Immunology & Inflammation; Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number903895-98-7
MW384.86
Purity98.84% (May vary between batches)
FormulaC20H21ClN4O2
SMILESCC(C)c1c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n(-c2ccccc2)n1C
TargetOthers
SolubilityDMSO:34.2 mg/mL (88.86 mM);10% DMSO+90% Corn Oil:2 mg/mL (5.2 mM)

Bioactivity

In Vitro
FPR Agonist 43 (10-5-107 nM) is actively potent in the cAMP assay in FPR2/ALX over-expressing CHO cells. FPR Agonist 43 is also active in the GTPγ binding assay (IC50=207±51 nM). FPR1 is the preferred receptor for FPR Agonist 43 in in both human neutrophils and possibly also in mouse cells.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

FPR Agonist 43, FPR1, FPR2/ALX
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

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1 mg
$ 80.00
5 mg
$ 140.00
1 ml x 10 mM (in DMSO)
$ 150.00
10 mg
$ 190.00
25 mg
$ 330.00
50 mg
$ 460.00
100 mg
$ 640.00
DispatchUsually dispatched within 3-5 working days
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