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FSG67

SKU: orb1689107

Description

FSG67 is a small molecule inhibitor of mitochondrial GPAT/GPAM. It is used in research to study hepatic regeneration, particularly by investigating its attenuation of liver repair after acetaminophen overdose through modulation of GSK3β and Wnt/β-catenin signaling pathways in experimental models.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number1158383-34-6
MW327.44
Purity99.76% (May vary between batches)
FormulaC16H25NO4S
SMILESO=C(O)C=1C=CC=CC1NS(=O)(=O)CCCCCCCCC
TargetOthers,Acyltransferase,Transferase
SolubilityDMSO:80 mg/mL (244.32 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (10.08 mM)

Bioactivity

Target IC50
GPAT:24 μM|oxidative metabolis:27.7 μM
In Vitro
FSG67 is a glycerol 3-phosphate acyltransferase (GPAT) inhibitor with an IC50 value of 24 μM.FSG67 was able to reduce the level of phosphorylation of GSK3β and associated signaling after paracetamol (acetaminophen) overdose. In mature adipocytes, FSG67 elevated oxidative metabolism in a dose-dependent manner with an IC50 of 27.7 μM.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

GPAT, FSG 67
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

5 mg
$ 290.00
1 ml x 10 mM (in DMSO)
$ 320.00
10 mg
$ 370.00
25 mg
$ 480.00
50 mg
$ 620.00
100 mg
$ 790.00
DispatchUsually dispatched within 5-10 working days
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