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GDC-0214

SKU: orb1297857

Description

GDC-0214 is an investigational, inhaled small molecule that selectively inhibits JAK1. It has been shown to reduce fractional exhaled nitric oxide (FeNO), a biomarker of airway inflammation, in preclinical research relevant to asthma and other respiratory diseases.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number1831144-46-7
MW612.03
Purity99.75%
FormulaC28H28ClF2N9O3
SMILESN(C(=O)C1=C2N(N=C1)C=CC=N2)C=3C(=NN(CC(=O)N4CCC(N(CCC#N)C)CC4)C3)C5=C(OC(F)F)C=CC(Cl)=C5
TargetJAK,STAT
SolubilityDMSO:9 mg/mL (14.71 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

GDC 0214, GDC0214, GDC-0214, JAK1
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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GDC-0214 (orb1297857)

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Available Sizes

Select a size below

1 mg
¥ 1,690.00
5 mg
¥ 3,250.00
1 ml x 10 mM (in DMSO)
¥ 4,160.00
10 mg
¥ 4,420.00
25 mg
¥ 6,760.00
50 mg
¥ 9,360.00
100 mg
¥ 12,480.00
200 mg
¥ 16,380.00
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