GFAP Antibody (PerCP)

SKU: orb150547

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Description

Mouse monoclonal to GFAP R416WT (PerCP). The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia..

Research Area

Neuroscience

Images & Validation

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Tested Applications	ICC, IF, IHC, WB
Dilution Range	WB (1:1000)
Reactivity	Human, Mouse, Rat
Application Notes	1 µg/ml was sufficient for detection of GFAP R416WT in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Key Properties

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Host	Mouse
Clonality	Monoclonal
Isotype	IgG1
Clone No.	N206B/9 (Formerly sold as S206B-9)
Immunogen	Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse. > 50% identity with other proteins (Vimentin, Desmin and Peripherin).
Target	GFAP
Molecular Weight	50kDa
Purification	Protein G Purified
Conjugation	PerCP

Storage & Handling

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Storage	Conjugated antibodies should be stored according to the product label
Buffer/Preservatives	95.46mM Phosphate, 2.48mM MES and 2mM EDTA
Concentration	1 mg/ml
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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GFAP, Glial fibrillary acidic protein, Intermediate filament protein, Astrocyte, GFAPL, DKFZp459C0729, MGC139638, FLJ45472, AI836096

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Quick Database Links

Gene Symbol

GFAP

UniProt

P14136

NCBI Gene ID

2670

RefSeq (Protein):NP_001124491.1

UniProt Details

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No UniProt data available

NCBI Gene Details

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No NCBI Gene data available

NCBI Reference Sequences

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Associated Accession Numbers

Curated reference sequences for the gene transcript and protein product

Protein	NP_001124491.1

Protocol Information

Western Blot (IB, immunoblot)

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IHC

Immunohistochemistry

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Immunofluorescence

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ICC

Immunocytochemistry

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Available Sizes

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100 μg

$ 660.00

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Usually dispatched within 2-3 weeks

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Applications:	FC, IF
Predicted Reactivity:	Bovine, Canine, Porcine, Rabbit, Sheep
Reactivity:	Human, Mouse, Rat
Species/Host:	Rabbit
Clonality:	Polyclonal
Conjugation:	PerCP/Cy7

Applications:	FC, IF
Predicted Reactivity:	Bovine, Canine, Porcine, Rabbit, Sheep
Reactivity:	Human, Mouse, Rat
Species/Host:	Rabbit
Clonality:	Polyclonal
Conjugation:	PerCP/Cy5.5

Applications:	FC, IF
Predicted Reactivity:	Bovine, Canine, Porcine, Rabbit, Sheep
Reactivity:	Human, Mouse, Rat
Species/Host:	Rabbit
Clonality:	Polyclonal
Conjugation:	PerCP

Applications:	FC, ICC
Predicted Reactivity:	Mouse, Rat
Reactivity:	Human
Species/Host:	Rabbit
Clonality:	Polyclonal
Conjugation:	PerCP/Cy5.5

GFAP Antibody (PerCP)

Description

Research Area

Images & Validation

Key Properties

Storage & Handling

Alternative Names

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