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GluR1 Antibody (APC)

SKU: orb150506

Description

Mouse monoclonal to GluA1 (APC). Glutamic acid is the major excitatory neurotransmitter in the mammalian central nervous system. Glutamate receptors are classified on the basis of their activation by different agonists (1-3). GluR1, human glutamate receptor type 1, is an integral membrane protein that is widely expressed in the human brain. The postsynaptic actions of glutamic acid are mediated by a variety of receptors that are named according to their selective agonists. GluR1 is known to bind a kainate subtype of agonist. It has been found that malfunctioning of the glutamatergic system may result in certain brain disorders and neurodegeneration..

Research Area

Cell Biology

Images & Validation

Tested ApplicationsICC, IF, IHC, WB
Dilution RangeWB (1:1000), ICC/IF (1:100)
ReactivityHuman, Mouse, Rat
Application Notes
1 µg/ml was sufficient for detection of GluA1 in 20 µg of mouse brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Key Properties

HostMouse
ClonalityMonoclonal
IsotypeIgG1
Clone No.N355/1
ImmunogenFusion protein amino acids 1-389 (extracellular N-terminus) of rat GluA1
TargetGluR1
Molecular Weight100kDa
PurificationProtein G Purified
ConjugationAPC

Storage & Handling

StorageConjugated antibodies should be stored according to the product label
Buffer/Preservatives95.46mM Phosphate, 2.48mM MES and 2mM EDTA
Concentration1 mg/ml
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

2900051M01Rik, AI853806, AMPA 1, AMPA selective glutamate receptor 1, GLUH 1, GLUH1, GLUR1, GLURA, Glr-1, Glr1, GluA1, GluR K1, GluR-A, GluR1, GluRA, GluRK1, Glur-1, Glur1, Glutamate receptor 1, Glutamate receptor ionotropic, Glutamate receptor ionotropic AMPA 1, Gria 1, HBGR1, HIPA, MGC13325, OTTHUMP00000160643, OTTHUMP00000165781, OTTHUMP00000224241, OTTHUMP00000224242, OTTHUMP00000224243, gluR-

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UniProt Details

No UniProt data available

NCBI Gene Details

No NCBI Gene data available

NCBI Reference Sequences

Associated Accession Numbers
Curated reference sequences for the gene transcript and protein product
ProteinNP_113796

Protocol Information

WB
Western Blot (IB, immunoblot)
View Protocol
IHC
Immunohistochemistry
View Protocol
IF
Immunofluorescence
View Protocol
ICC
Immunocytochemistry
View Protocol

Available Sizes

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100 μg
$ 660.00
Choose Conjugation or Carrier Free Version
Free Secondary Antibody (20 ul)0/0

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DispatchUsually dispatched within 2-3 weeks
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