Glucocorticoid receptor agonist-2

SKU: orb1982705

Description

Glucocorticoid receptor agonist-2 (compound 21) is a potent GR agonist with an IC50 of 6.6 nM, used as a reference standard for compounds like ABBV-3373. It is a key building block in the development of anti-inflammatory antibody-drug conjugates (ADCs) for research in immunology and inflammation.

Research Area

Metabolism Research

Images & Validation

−

Key Properties

−

CAS Number	2166378-92-1
MW	607.64
Formula	C₃₄H₃₅F₂NO₇
SMILES	C(CO)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(O[C@H](O2)C4=CC=C(OC5=CC(N)=CC=C5)C=C4)[H])([C@]6([C@](F)([C@@H](O)C3)[C@]7(C)C([C@@H](F)C6)=CC(=O)C=C7)[H])[H]
Target	Glucocorticoid Receptor,ADC Cytotoxin

Storage & Handling

−

Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Compound Identifiers

PubChem CID

134491916 ↗

Key Properties

−

No computed properties available.

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols