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Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br

SKU: orb2279094

Description

Glucocorticoid Receptor Agonist-1 Phosphate (Gly-Glu-Br) is a phosphate-containing linker-payload used in the construction of antibody-drug conjugates (ADCs) such as ABBV-154. It is applied in oncology research for developing targeted therapeutics, with its utility demonstrated in preclinical in vitro and in vivo studies for selective drug delivery.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2344809-82-9
MW956.77
FormulaC44H51BrN3O14P
SMILESC(COP(=O)(O)O)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(O[C@H](O2)C4=CC=C(CC5=CC(NC([C@@H](NC(CNC(CBr)=O)=O)CCC(O)=O)=O)=CC=C5)C=C4)[H])([C@]6([C@]([C@@H](O)C3)([C@]7(C)C(CC6)=CC(=O)C=C7)[H])[H])[H]
TargetDrug-Linker Conjugates for ADC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information