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Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Mal

SKU: orb2564821

Description

This compound acts as a glucocorticoid receptor agonist and is specifically designed as a phosphate-protected drug-linker for antibody-drug conjugates (ADCs). It has been utilized in the synthesis of anti-CD40 ADCs for research, enabling the study of targeted glucocorticoid activity in both in vitro and in vivo models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2345732-83-2
MW915.87
FormulaC46H50N3O15P
SMILESC(COP(=O)(O)O)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(O[C@H](O2)C4=CC=C(CC5=CC(NC([C@@H](NC(CN6C(=O)C=CC6=O)=O)CCC(O)=O)=O)=CC=C5)C=C4)[H])([C@]7([C@]([C@@H](O)C3)([C@]8(C)C(CC7)=CC(=O)C=C8)[H])[H])[H]
TargetDrug-Linker Conjugates for ADC,Glucocorticoid Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information