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GluN2B-NMDAR antagonist-2

SKU: orb3133770

Description

GluN2B-NMDAR antagonist-2 (compound S-58) is an effective and selective NMDAR-GluN2B antagonist that can cross the blood-brain barrier, with an IC50 value of 74.01 nM. It exhibits mild cytotoxicity and reduces both infarct size and neurological deficit scores in the brain, indicating its potential for stroke research.

Research Area

Neuroscience, Neuroscience; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery

Images & Validation

Key Properties

FormulaC24H25Cl2N3O3
TargetiGluR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information