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Glycosyltransferase-IN-2

SKU: orb3173159

Description

Glycosyltransferase-IN-2 (Compound 20) is an inhibitor of glycosyltransferase with broad-spectrum antiviral activities against coronaviruses. It shows IC50 values of 11.3 μM for MHV, 5.5 μM for HCoV-NL63, and approximately 16.2 μM for SARS-CoV-2. This compound can interfere with coronavirus infectivity, alter viral protein glycosylation, inhibit interaction with the ACE2 receptor, and suppress secretion of cytotoxic viral particles (SC-VLP) and RNA replication. Glycosyltransferase-IN-2 is utilized in coronavirus infection research.

Images & Validation

Key Properties

TargetSARS-CoV,Transferase,Angiotensin-converting Enzyme (ACE),DNA/RNA Synthesis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information