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GPI-1485

SKU: orb1297859

Description

GPI-1485 (GM1485) is a non-immunosuppressive immunophilin ligand. It has been studied in models of cerebral ischemia for its potential to enhance neurofunctional recovery and promote neural regeneration following stroke, supporting research in neuroprotection and CNS repair.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number186268-78-0
MW241.28
Purity99.80% (May vary between batches)
FormulaC12H19NO4
SMILESC(C(C(CC)(C)C)=O)(=O)N1[C@H](C(O)=O)CCC1
TargetOthers,FKBP
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (13.68 mM);DMSO:95 mg/mL (393.73 mM)

Bioactivity

In Vivo
GPI-1485 (5 mg/kg; intraperitoneal injection; 6-week period of daily) improved long-term neurological recovery in rats
In Vitro
GPI-1485 induced cellular reprogramming and neural cell induction in normal human dermal fibroblasts (NHDF) .

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

regeneration, stroke, Inhibitor, ligand, immunophilin, inhibit, neural, neurofunctional, GM 1485, GM1485, GM-1485, GPI-1485, GPI1485, GPI 1485
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

GPI-1485 (orb1297859)

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Available Sizes

Select a size below

1 mg
¥ 1,300.00
5 mg
¥ 2,470.00
1 ml x 10 mM (in DMSO)
¥ 2,600.00
10 mg
¥ 3,380.00
25 mg
¥ 5,720.00
50 mg
¥ 8,190.00
100 mg
¥ 11,440.00
200 mg
¥ 16,380.00
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