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GPR139 agonist-2

SKU: orb1942500

Description

GPR139 agonist-2 (Compound 20a) is a potent small molecule agonist with an EC₅₀ of 24.7 nM. It has shown efficacy in preclinical murine models, rescuing social interaction and cognitive deficits, supporting its investigation for schizophrenia-related research in both in vitro and in vivo applications.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2983118-29-0
MW380.32
FormulaC17H15F3N4O3
SMILESO=C1N2C(C=NN1CC(N[C@@H](C)C3=CC=C(OC(F)(F)F)C=C3)=O)=CC=C2
TargetOthers,GPCR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information