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GPR183 inverse agonist-1

SKU: orb3136429

Description

GPR183 inverse agonist-1 (Compound 78) is an inverse agonist of GPR183. It inhibits GPR183-mediated Gi activation and β-arrestin2 recruitment while blocking PBMC migration. This compound is utilized in research concerning inflammation, autoimmune, and cancer-related diseases.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2380033-51-0
MW442.31
FormulaC20H20BrN5O2
SMILESO=C1C=CC(=NN1CC2CCN(C(=O)C3=CC=C(Br)C=C3)CC2)N4N=CC=C4
TargetArrestin,EBI2/GPR183

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information