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GS-441524 HCl

SKU: orb1739823

Description

GS-441524 is the active metabolite of Remdesivir and a potent nucleoside analog inhibitor of viral RNA-dependent RNA polymerase. It demonstrates strong antiviral activity against feline infectious peritonitis virus (FIPV) both in vitro (e.g., CRFK cells and feline macrophages) and in vivo, with an EC50 of 0.78 µM, and shows low cytotoxicity at concentrations up to 100 µM.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology

Images & Validation

Key Properties

CAS Number2378280-82-9
MW327.72
FormulaC12H14ClN5O4
SMILESC(#N)[C@]1(O[C@H](CO)[C@@H](O)[C@H]1O)C=2N3C(=CC2)C(N)=NC=N3.Cl
TargetOthers,DNA/RNA Synthesis,SARS-CoV

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information

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25 mg
$ 1,560.00
50 mg
$ 2,020.00
100 mg
$ 2,540.00
DispatchUsually dispatched within 6-8 weeks
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