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GSK3004774

SKU: orb1709532

Description

GSK3004774 is a nonabsorbable, potent agonist of the Calcium-Sensing Receptor (CaSR), exhibiting pEC50 values of 7.3, 6.6, and 6.5 for human, mouse, and rat receptors, respectively. This compound is a valuable research tool for investigating CaSR function in gastrointestinal physiology, including studies on gastric acid secretion and intestinal phosphate handling in both in vitro and in vivo models.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2138814-32-9
MW528.68
FormulaC32H40N4O3
SMILES[C@@H](N[C@@H]1CN(CC1)C2=CC=C(C(NCCCN3CCC(C(O)=O)CC3)=O)C=C2)(C)C=4C5=C(C=CC4)C=CC=C5
TargetOthers,CaSR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

GSK3004774 (orb1709532)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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