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GTS-21 dihydrochloride

SKU: orb1305200

Description

GTS-21 dihydrochloride (DMBX-anabaseine) is a selective agonist for neuronal nicotinic acetylcholine receptors (nAChRs). It is widely used in neuroscience research to study cognitive function, neuroprotection, and receptor pharmacology in both in vitro and in vivo experimental models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number156223-05-1
MW381.30
Purity98.54% (May vary between batches)
FormulaC19H20N2O2·2HCl
SMILESCOC(C=C(C=C1)OC)=C1/C=C2C(C3=CN=CC=C3)=NCCC/2.Cl.Cl
Target5-HT Receptor,AChR
SolubilityDMSO:15 mg/mL (39.34 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.25 mM)

Bioactivity

Target IC50
α4β2 (human):20 nM (Ki)|5-HT3A receptor:3.1 μM (IC50)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

DMXB-A, DMBX-anabaseine, cognition, 5HT Receptor, 5HTReceptor, 5-hydroxytryptamine Receptor, 5-HT Receptor, anti?inflammatory, nAChR, Nicotinic acetylcholine receptors, lung, inhibit, Inhibitor, injury, GTS 21, GTS 21 dihydrochloride, GTS 21 Dihydrochloride, GTS21, GTS-21, GTS21 dihydrochloride, GTS21 Dihydrochloride, GTS-21 Dihydrochloride, fibrosis, Serotonin Receptor, pulmonary, α4β2 nAChR
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

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5 mg
$ 90.00
1 ml x 10 mM (in DMSO)
$ 100.00
10 mg
$ 120.00
25 mg
$ 160.00
50 mg
$ 190.00
100 mg
$ 270.00
200 mg
$ 390.00
500 mg
$ 620.00
DispatchUsually dispatched within 3-5 working days
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