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GYKI 52466 HCl

SKU: orb1739417

Description

GYKI 52466 is a selective allosteric antagonist of AMPA receptors, inhibiting AMPA- and kainate-induced currents in vitro (IC50 = 7.5 µM and 11 µM, respectively). In vivo, it demonstrates anticonvulsant activity in a 4-AP seizure model and is neuroprotective in a rat global ischemia model, highlighting its utility in neuroscience research.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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GYKI 52466 HCl

Key Properties

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CAS Number192065-56-8
MW329.784
FormulaC17H16ClN3O2
SMILESCl.CC1=NN=C(c2ccc(N)cc2)c2cc3OCOc3cc2C1
TargetiGluR,Others

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Compound Identifiers

PubChem CID
10042240 ↗

Key Properties

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No computed properties available.

Protocol Information

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10 mg
$ 520.00
DispatchUsually dispatched within 6-8 weeks
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