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H3R antagonist 5

SKU: orb2944544

Description

Compound 1b is a potent and selective histamine H3 receptor inverse agonist (IC50 = 0.54 nM) with demonstrated blood-brain barrier penetration. This makes it a valuable research tool for in vitro and in vivo studies of central nervous system functions, such as sleep-wake regulation and cognitive processes.

Research Area

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number879368-27-1
MW400.511
FormulaC23H32N2O4
SMILESO=C1O[C@]2(C=3C1=CC(OC)=CC3)CC[C@@H](C(N(CCN4CCCCC4)C)=O)CC2
TargetHistamine Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

H3R antagonist 5 (orb2944544)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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