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HCAR2 agonist 1

SKU: orb1942533

Description

HCAR2 agonist 1 (Compound 9n) is a G i-biased allosteric modulator that activates G i signaling, reducing pro-inflammatory cytokine mRNA and demonstrating anti-inflammatory effects. It potentiates orthosteric agonists in a colitis mouse model, applicable for in vitro and in vivo inflammation research.

Research Area

Pharmacology & Drug Discovery, Pharmacology & Drug Discovery; Cell Biology

Images & Validation

Key Properties

CAS Number1066676-21-8
MW428.53
FormulaC26H28N4O2
SMILESCC=1N2C(=C(C=N2)C3=CC=C(C(C)C)C=C3)N=CC1C(N[C@@H](COC4=CC=CC=C4)C)=O
TargetOthers,HCAR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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25 mg
$ 2,860.00
50 mg
$ 3,520.00
100 mg
$ 4,440.00
DispatchUsually dispatched over 10 weeks
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