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HDAC6-IN-49

SKU: orb2665089

Description

HDAC6-IN-49 is a potent and selective HDAC6 inhibitor (IC50=0.012 µM) with additional activity against MAO-B, ChE, H3R, and 5-HT6R. It demonstrates neuroprotective effects in SH-SY5Y cells and improves cognitive and motor function in Drosophila and C. elegans models of neurodegenerative disease.

Research Area

Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

Target5-HT Receptor|||Histamine Receptor|||HDAC|||Monoamine Oxidase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information