HDAC8 (C) Antibody, Rabbit Polyclonal

SKU: orb67063

Description

Rabbit polyclonal to HDAC8.Histone deacetylase 8 (HDAC8) belongs to the histone deacetylase family. HDAC8 is responsible forthe deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 andH4). Histone deacetylation gives a tag for epigenetic repression and plays an important role intranscriptional regulation, cell cycle progression and developmental events. Histone deacetylases actvia the formation of large multiprotein complexes. It may play a role in smooth muscle cell contractility.

Research Area

Cardiovascular Disease, Epigenetics, Stem Cells

Images & Validation

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Tested Applications	WB
Dilution range	WB:1:1000-1:5000
Reactivity	Human

Key Properties

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Host	Rabbit
Clonality	Polyclonal
Immunogen	C-terminal region of human HDAC8
Molecular Weight	42
Purity	Affinity purification
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives	0.01% NaN3
Disclaimer	For research use only

Alternative Names

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anti-HDAC8 antibody,anti-Histone deacetylase 8 antibody,anti-HDACL1 antibody,anti-CDA07 antibody

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Western blot analysis of total cell extracts from human Hela using HDAC8 antibody

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UniProt

Q9BY41

UniProt Details

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No UniProt data available

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Protocol Information

Western Blot (IB, immunoblot)

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