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HDGFRP2/PSIP1-IN-1

SKU: orb2665004

Description

Compound BPP (HDGFRP2/PSIP1-IN-1) is a dual PWWP domain inhibitor targeting HDGFRP2 (Kd=7 µM) and PSIP1 (Kd=27 µM), which has shown activity against Diffuse Intrinsic Pontine Glioma (DIPG) in research models. This small molecule is a tool for investigating chromatin reader function in oncology, particularly for in vitro binding studies and cellular mechanism-of-action experiments.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Images & Validation

Key Properties

CAS Number166196-54-9
MW224.06
FormulaC8H6BrN3
SMILESBrC1=CNN=C1C=2C=CN=CC2
TargetDNA/RNA Synthesis,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information