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Human Her2 & ErbB3 Protein, Fc Tag

SKU: orb1786196

Description

Human Her2 & ErbB3 Protein, Fc Tag & Fc Tag is expressed from human 293 cells (HEK293). It contains AA Thr 23 - Thr 652 & Ser 20 - Thr 643 (Accession # P04626 & P21860).

Research Area

Signal Transduction

Images & Validation

Application Notes
Human Her2 & ErbB3 Protein, Fc Tag&Fc Tag, produced by co-expression of HER2 and ErbB3, has a calculated MW of 95.9 kDa (HER2) and 94.9 kDa (ErbB3). Subunit HER2 is fused with a human IgG1 Fc fragment at the C-terminus and subunit ErbB3 is fused with a human IgG1 Fc fragment at the C-terminus. The protein migrates as 110-130 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

Expression SystemHEK293
TargetHer2 & ErbB3
ReactivityHuman
TagC-Fc | C-Fc
Expression RegionThr 23 - Thr 652 & Ser 20 - Thr 643
Endotoxins1.0 EU per μg
ConjugationUnconjugated
MW95.9 kDa & 94.9 kDa
Purity90%

Storage & Handling

Storage-20°C
Form/AppearancePowder
Buffer/Preservatives50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
Expiration Date6 months from date of receipt.
DisclaimerFor research use only
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UniProt Details

No UniProt data available

NCBI Reference Sequences

Associated Accession Numbers
Curated reference sequences for the gene transcript and protein product
RefSeqP04626, P21860

Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
View Guide