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Human PCSK9 Protein, Fc Tag

SKU: orb545756

Description

Human PCSK9, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Gln 31 - Gln 692 (Accession # Q8NBP7-1).

Research Area

Disease Biomarkers

Images & Validation

Application Notes
This protein carries a human IgG1 Fc tag at the C-terminus. This protein undergoes autocatalytic cleavage to release the pro-peptide and mature chain. The pro-peptide and mature chain are associated through non‑covalent interactions and with a calculated MW of 13.8 kDa and 83.7 kDa respectively. The protein migrates as 16 kDa and 100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

Expression SystemHEK293
TargetPCSK9
ReactivityHuman
TagC-Fc
Molecular Weight13.8 kDa and 83.7 kDa
Expression RegionGln 31 - Gln 692
Purity90%
Endotoxins1.0 EU per μg
ConjugationUnconjugated

Storage & Handling

Storage-20°C
Form/AppearancePowder
Buffer/PreservativesPBS, pH 7.4
Expiration Date6 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • Human PCSK9 Protein, hFc Tag [orb1173897]

    Unconjugated

    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

    The protein has a predicted molecular mass of 97.2 kDa after removal of the signal peptide.The apparent molecular mass of PCSK9-hFc is approximately 100-130 kDa due to glycosylation.

    Mammalian

    10 μg, 100 μg, 50 μg
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UniProt Details

No UniProt data available

NCBI Reference Sequences

Associated Accession Numbers
Curated reference sequences for the gene transcript and protein product
RefSeqQ8NBP7

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Protocol Information

Human PCSK9 Protein, Fc Tag (orb545756)

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50 μg
¥ 7,670.00
1 mg
¥ 49,660.00
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