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Human Prostatic Acid Phosphatase Protein, His Tag (active enzyme, MALS verified)

SKU: orb3158048

Description

Prostatic acid phosphatase also know as acid phosphatase 3 (ACP3), it is a non-specific tyrosine phosphatase that acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling. In addition to its tyrosine phosphatase activity has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor.

Research Area

Immunology & Inflammation

Images & Validation

Application Notes
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 42.5 kDa. The protein migrates as 45-50 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

Expression SystemHEK293
TargetProstatic Acid Phosphatase
ReactivityHuman
TagC-10×His
Molecular Weight42.5 kDa
Expression RegionLys 33 - Lys 382
Purity90%
Endotoxins1.0 EU per μg
ConjugationUnconjugated

Storage & Handling

Storage-70°C
Form/AppearanceLiquid
Buffer/Preservatives100 mM NaAC, pH 5.0
Expiration Date6 months from date of receipt.
Dry Ice ShippingPlease note: This product requires shipment on dry ice. A dry ice surcharge will apply.
DisclaimerFor research use only
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UniProt Details

No UniProt data available

NCBI Reference Sequences

Associated Accession Numbers
Curated reference sequences for the gene transcript and protein product
RefSeqP15309

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Protocol Information

Human Prostatic Acid Phosphatase Protein, His Tag (active enzyme, MALS verified) (orb3158048)

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