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Human USP7 Protein, His Tag

SKU: orb3158049

Description

The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental

Research Area

Epigenetics & Chromatin

Images & Validation

Application Notes
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 130.2 kDa. The protein migrates as 130 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

Key Properties

Expression SystemInsectCells
TargetUSP7
ReactivityHuman
TagN-10×His
Expression RegionAsn 2 - Asn 1102
Endotoxins1.0 EU per μg
ConjugationUnconjugated
MW130.2 kDa
Purity85%

Storage & Handling

Storage-70°C
Form/AppearanceLiquid
Buffer/Preservatives50 mM HEPES, 100 mM NaCl, pH 8.0
Expiration Date6 months from date of receipt.
Dry Ice ShippingPlease note: This product requires shipment on dry ice. A dry ice surcharge will apply.
DisclaimerFor research use only

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UniProt Details

No UniProt data available

NCBI Reference Sequences

Associated Accession Numbers
Curated reference sequences for the gene transcript and protein product
RefSeqQ93009

Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
View Guide