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Isoliquiritin

SKU: orb1222155

Description

Isoliquiritin has antitussive effects. Isoliquiritin has antidepressant-like effects. Isoliquiritin, liquiritin and isoliquirigenin inhibits the p53-dependent pathway and shows crosstalk between Akt activities.

Images & Validation

Key Properties

CAS Number5041-81-6
MW418.39
Purity>98% (HPLC)
FormulaC21H22O9
SMILESC1=CC(=CC=C1C=CC(=O)C2=C(C=C(C=C2)O)O)OC3C(C(C(C(O3)CO)O)O)O
Targetp53
SolubilityIn Vitro: DMSO : 125 mg/mL (298.76 mM)

Bioactivity

In Vivo
Animal model: Mice in Forced Swimming Test (FST) and the Tail Suspension Test (TST). Dosage: 10, 20 and 40 mg/kg. Administration: oral gavage. Result: Reduced the immobility time in the FST and TST in mice. Increased 5-HT and NE level and Reduced the ratio of 5-HIAA/5-HT in the hippocampus, hypothalamus and cortex.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Isoliquiritin (orb1222155)

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200 mg
500 mg
5 mg
¥ 1,690.00
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¥ 2,470.00
25 mg
¥ 4,550.00
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¥ 6,630.00
100 mg
¥ 9,620.00