Isovaleryl-L-carnitine (chloride)

SKU: orb3177634

Description

Isovaleryl-L-carnitine is a naturally occurring acylcarnitine that is formed via metabolic conversion of L-leucine. It increases survival and decreases apoptosis in hepatocyte growth factor-deprived murine C2.8 hepatocytes when used at a concentration of 1 mM. Isovaleryl-L-carnitine inhibits amino acid deprivation-induced proteolysis and autophagy in isolated perfused rat liver when used at concentrations of 77 and 100 μM, respectively. Increased levels of isovaleryl carnitine are associated with isovaleryl-CoA dehydrogenase deficiency (isovaleric acidemia).

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Key Properties

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CAS Number	139144-12-0
MW	281.78
Purity	99.95% (May vary between batches)
Formula	C₁₂H₂₄ClNO₄
SMILES	[C@H](OC(CC(C)C)=O)(C[N+](C)(C)C)CC(O)=O.[Cl-]
Target	Proteasome,Others,Endogenous Metabolite

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Proteasome,Others,Endogenous Metabolite

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