Itacitinib adipate

SKU: orb1709391

Description

Itacitinib adipate is a selective, orally available JAK1 inhibitor. Its efficacy and safety have been evaluated in a Phase II clinical trial for myelofibrosis. This small molecule is used in research to investigate JAK-STAT signaling in hematological cancers and inflammatory diseases through in vitro and in vivo studies.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

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Key Properties

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CAS Number	1334302-63-4
MW	699.66
Formula	C₃₂H₃₃F₄N₉O₅
SMILES	N#CCC1(N2N=CC(=C2)C=3N=CN=C4NC=CC43)CN(C1)C5CCN(C(=O)C=6C=CN=C(C6F)C(F)(F)F)CC5.O=C(O)CCCCC(=O)O
Target	JAK,Phosphatase

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

67390313 ↗

Key Properties

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No computed properties available.

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